Endocrine Abstracts

Introduction: Paget’s disease of bone (PDB) is the second-most-common metabolic bone disease, after osteoporosis, affecting about 3% of the population at age over 40 years. This disease is characterized by excessive and abnormal bone remodeling due to increased bone resorption followed by disorganized bone formation.This paper will include a case report and a review of PDB epidemiology and pathophysiology, complications and clinical findings, indica...

Clear cell renal carcinoma (CCRC) is a tumor with great metastatic capacity, although the presence of metastases in the thyroid gland is very uncommon. Therefore it is important to know the oncological background of the patient and to perform a complete immunohistochemical analysis of the thyroid lesion to obtain a correct diagnosis. Thyroidectomy can be considered in patients with no other metastasis or in those who present compressive symptoms as a palliative measure. We pre...

Objective: The latest studies on Graves’ ophthalmopathy (GO) emphasize the importance of the orbital adipose tissue and fibroblasts in the pathogenesis of the disease by secreting proinflammatory cytokines. In vitro, these cytokines were proved to have a major role in the maintenance and progress of inflammation in the orbit. The aim of this study was to investigate serum cytokine levels in patients with GO.Materials and methods: Serum interl...